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زیست شناسی::
سلول پیشساز
Endodermal and ectodermal cetls are unipotent progenitor cells that divide continuously, producing more lineage-restricted epithelia.
These progenitor cells form a mass of proliferative cells directly beneath the AEC that constitutes the blastema (red).
Thus, the blastema is not a collection of unspecified multipotent progenitor cells.
Rather, the cells retain their specification, and the blastema is a heterogeneous assortment of restricted progenitor cells.
Some contributions may occur from as yet unidentified resident stem/progenitor cells capable of generating osteoblasts in the absence of any committed bone cells (Singh et al. 2012).
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