1 زیست شناسی:: سلول پیشساز
Endodermal and ectodermal cetls are unipotent progenitor cells that divide continuously, producing more lineage-restricted epithelia. These progenitor cells form a mass of proliferative cells directly beneath the AEC that constitutes the blastema (red). Thus, the blastema is not a collection of unspecified multipotent progenitor cells. Rather, the cells retain their specification, and the blastema is a heterogeneous assortment of restricted progenitor cells. Some contributions may occur from as yet unidentified resident stem/progenitor cells capable of generating osteoblasts in the absence of any committed bone cells (Singh et al. 2012).
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